Meiogenix Publishes Groundbreaking Study on Targeted Recombination in Rice Using dCas9-SPO11-1

Paris, France – May 31, 2025 –

Meiogenix, Inc, a biotechnology company pioneering targeted recombination to unlock the full genetic potential of crops, is proud to announce the publication of its latest peer-reviewed research in Frontiers in Plant Science. The study demonstrates how the use of dCas9-SPO11-1 can locally stimulate meiotic recombination in rice, offering new tools to accelerate breeding and enhance crop performance.

This breakthrough builds on Meiogenix’s mission to develop precise, biology-based solutions that enable the next generation of climate-resilient and biodiverse crops. The rice study represents a significant milestone in applying targeted recombination to major food crops, and showcases the potential of this approach to address some of the most pressing challenges in global agriculture, from productivity and adaptability to sustainability and food security.

“This publication marks a major milestone for Meiogenix and modern plant breeding. Unlocking and redirecting recombination holds immense promise for tackling some of agriculture’s toughest challenges.” said Dr. Gaganpreet Sidhu, Chief Technology Officer of Meiogenix.  “This is just the beginning for what the Meiogenix technology platform has to offer, and I am proud to be part of the team that is leading this effort forward.”

The study was led by a multidisciplinary team of researchers and collaborators from Meiogenix, CIRAD, Institut Curie, and partner institutions. Special recognition goes to Ian Fayos, Léo Herbert, Emmanuel Guiderdoni, Alain Nicolas, Luc Mathis, Aurore Vernet, Jérémy Di Mattia, PhD, Anne-Cécile Meunier, Julien Frouin, and Minghui Wang, whose contributions were instrumental in this achievement.

Read the full article here:

Frontiers in Plant Science – dCas9-SPO11-1 locally stimulates meiotic recombination in rice

“This is not just a scientific achievement. It’s a foundational step toward real-world impact in agriculture,” said Ricardo Garcia de Alba, CEO of Meiogenix. “Targeted recombination can unlock diversity that would be otherwise unavailable tobreeders. We are proud to contribute to the science that makes this vision a reality.”

Meiogenix continues to expand its research and development pipeline across crops such as corn, tomato, and rice, building strong collaborations with academic institutions and industry leaders to bring targeted recombination technologies to the field.

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About Meiogenix
Meiogenix is an agriculture biotech company that develops disruptive new products based on Chromosome Editing. By unlocking the natural genetic diversity of crops, Meiogenix expands the biodiversity that can be used by farmers to address global climate, sustainability and food challenges.

Left to Right
Ian Fayos, Ricardo Garcia de Alba, Emmanuel Guiderdoni, Léo Herbert, Mary Beth Miranda

For more information on Meiogenix, please visit https://meiogenix.com/